In order to evaluate our design, we’re applying three different kinds of testing and using a combination of software and physical prototyping.
Mechanics: ANSYS Finite Element Analysis
Using computer simulations of the vessel and the stent, we can test the stresses and strains in the stent material and in the tissue in response to different forces such as being compressed, bent, or collapsed to fit in a delivery catheter.
Model of the vessel and a section of the stent being compressed
Model of the stent being bent around a mandrel
Fluids: ESI Computational Fluid Dynamics
Models of the stent and vessel surfaces can be placed in a simulated flow field in order to examines how fluid moves around the stent. We are looking at the stress on the vessel and on the stent as well as the velocity of the blood.
Stresses on the surface of the stent
Stresses on the vessel
Benchtop: 3D Printed Stent Model and Flow Loop
We are building a prototype of the stent to test for hemolysis, or damage to cells that causes them to break open, using a 3D printer. We can then attach this to tubing and use a pump to make an artificial circulatory system.
3D printed model of the stent inside of the vessel at a 2:1 scale
Flow loop made up of the stent model, roller pump, and heated water bath
After passing bovine blood through the loop we are measuring the amount of hemoglobin released into the plasma due to hemolysis
