{"id":70,"date":"2023-09-09T23:56:31","date_gmt":"2023-09-09T23:56:31","guid":{"rendered":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/?page_id=70"},"modified":"2023-09-11T23:49:29","modified_gmt":"2023-09-11T23:49:29","slug":"introduction","status":"publish","type":"page","link":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/introduction\/","title":{"rendered":"Background"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Chronic Kidney Disease (CKD) <\/h2>\n\n\n\n<p>Stage 5 of chronic kidney disease (CKD) are one of the leading causes of mortality affecting about 10% of the worldwide population. 38% of patients with CKD are people aged 65 years or older.<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35529086\/\" data-type=\"URL\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35529086\/\">1<\/a><\/sup><\/p>\n\n\n\n<p>CKD patients have a glomerular filtration rate (GFR) of less than 60mL\/min\/1.73m<sup>2<\/sup>. Another indicator is the levels of albumin; albuminuria of at least 30 mg per 24 hours urine or more than 30mg\/g of albumin in an isolated urine sampled adjusted by urinary creatine. CKD is one of the biggest attributer to cases diabetes and\/or hypertension.<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31939529\/\" data-type=\"URL\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31939529\/\">2<\/a><\/sup><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"850\" height=\"536\" src=\"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-content\/uploads\/sites\/249\/2023\/09\/introduction-ckd.png\" alt=\"\" class=\"wp-image-72\" srcset=\"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-content\/uploads\/sites\/249\/2023\/09\/introduction-ckd.png 850w, https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-content\/uploads\/sites\/249\/2023\/09\/introduction-ckd-300x189.png 300w, https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-content\/uploads\/sites\/249\/2023\/09\/introduction-ckd-768x484.png 768w\" sizes=\"auto, (max-width: 850px) 100vw, 850px\" \/><\/figure>\n\n\n\n<p>Image 1: Stages of Chronic Kidney Disease according to glomerular filtration and albumin levels. <\/p>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\">CKD Assessment:<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Measurement of creatine and GFR.<\/li>\n\n\n\n<li>albuminuria calculation by measuring the ratio of albumin\/creatine in the urine of an isolated sample.<\/li>\n\n\n\n<li>Imaging exam.<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6656849\/\" data-type=\"URL\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6656849\/\">3<\/a><\/sup><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\" style=\"font-style:normal;font-weight:300;text-transform:capitalize\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-purple-color\">CKD patient are test strip tested at least once a year while anemic CKD patients are tested at least twice a year. <\/mark><\/em><sup><a href=\"https:\/\/doi.org\/10.1038\/ki.2013.444\" data-type=\"URL\" data-id=\"https:\/\/doi.org\/10.1038\/ki.2013.444\">4<\/a><\/sup><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Type I Diabetes (T1D)<\/h2>\n\n\n\n<p>Type I diabetes is characterized but the autoimmune destruction of insulin-producing \u03b2 cells in the pancreatic islets over time.<sup><a href=\"https:\/\/doi.org\/10.1503\/cmaj.060244\" data-type=\"URL\" data-id=\"https:\/\/doi.org\/10.1503\/cmaj.060244\">5<\/a><\/sup> Currently, 0.55% of U.S adults had diagnosed type 1 diabetes, representing 1.3 million adults.<sup><a href=\"http:\/\/dx.doi.org\/10.15585\/mmwr.mm6712a2\" data-type=\"URL\" data-id=\"http:\/\/dx.doi.org\/10.15585\/mmwr.mm6712a2\">6<\/a><\/sup><\/p>\n\n\n\n<p>The development of T1D has three stages. Stage 1 is asymptomatic with a presence of more than 2 pancreatic antibodies. Stage 2 consists of impaired fasting glucose between 1oo to 125mg\/dL or 5.7% to 6.4% of blood sugar attached to the hemoglobin. Finally, stage 3 is also known as hyperglycemia where the random glucose is greater than 200 mg\/dL, fasting glucose is greater than 126 mg\/dL, and the blood sugar in hemoglobin is greater than 6.5%.<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507713\/\" data-type=\"URL\" data-id=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507713\/\">7<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\">T1D Assessment:<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Hemoglobin A1c testing (HbA1c) to measure the amounts of sugar blood in hemoglobin every 3 to 6 months.<\/li>\n\n\n\n<li>Yearly lipid profile.<\/li>\n\n\n\n<li>Urine albumin to creatine ratio.<\/li>\n\n\n\n<li>eGFR and serum creatinine.<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507713\/\" data-type=\"URL\" data-id=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507713\/\">7<\/a><\/sup><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\" style=\"font-style:normal;font-weight:300\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-purple-color\"><em>Type 1 diabetic patients are test strip tested at least 4 times a day and glucose monitored every 5 to 15 minutes a day.<sup><a href=\"https:\/\/doi.org\/10.1177\/1932296814546025\" data-type=\"URL\" data-id=\"https:\/\/doi.org\/10.1177\/1932296814546025\">8<\/a><\/sup> <\/em><\/mark><\/h2>\n\n\n\n<!--nextpage-->\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\"><strong><em>Citations <\/em><\/strong><\/h2>\n\n\n\n<p>[1] Kovesdy C. P. (2022). Epidemiology of chronic kidney disease: an update 2022.&nbsp;<em>Kidney international supplements<\/em>,&nbsp;<em>12<\/em>(1), 7\u201311. <a href=\"https:\/\/doi.org\/10.1016\/j.kisu.2021.11.003\">https:\/\/doi.org\/10.1016\/j.kisu.2021.11.003<\/a><\/p>\n\n\n\n<p>[2] Ammirati A. L. (2020). Chronic Kidney Disease.&nbsp;<em>Revista da Associacao Medica Brasileira (1992)<\/em>,&nbsp;<em>66Suppl 1<\/em>(Suppl 1), s03\u2013s09. <a href=\"https:\/\/doi.org\/10.1590\/1806-9282.66.S1.3\">https:\/\/doi.org\/10.1590\/1806-9282.66.S1.3<\/a><\/p>\n\n\n\n<p>[3] Ginsberg, J. M., Chang, B. S., Matarese, R. A., &amp; Garella, S. (1983). Use of single voided urine samples to estimate quantitative proteinuria.&nbsp;<em>The New England journal of medicine<\/em>,&nbsp;<em>309<\/em>(25), 1543\u20131546. <a href=\"https:\/\/doi.org\/10.1056\/NEJM198312223092503\">https:\/\/doi.org\/10.1056\/NEJM198312223092503<\/a><\/p>\n\n\n\n<p>[4] Levin, A., &amp; Stevens, P. E. (2014). Summary of KDIGO 2012 CKD Guideline: behind the scenes, need for guidance, and a framework for moving forward.&nbsp;<em>Kidney international<\/em>,&nbsp;<em>85<\/em>(1), 49\u201361. <a href=\"https:\/\/doi.org\/10.1038\/ki.2013.444\">https:\/\/doi.org\/10.1038\/ki.2013.444<\/a><\/p>\n\n\n\n<p>[5] Gillespie K. M. (2006). Type 1 diabetes: pathogenesis and prevention.&nbsp;<em>CMAJ : Canadian Medical Association journal = journal de l&#8217;Association medicale canadienne<\/em>,&nbsp;<em>175<\/em>(2), 165\u2013170. <a href=\"https:\/\/doi.org\/10.1503\/cmaj.060244\">https:\/\/doi.org\/10.1503\/cmaj.060244<\/a><\/p>\n\n\n\n<p>[6] Bullard KM, Cowie CC, Lessem SE, et al. Prevalence of Diagnosed Diabetes in Adults by Diabetes Type \u2014 United States, 2016. MMWR Morb Mortal Wkly Rep 2018;67:359\u2013361. DOI:&nbsp;<a rel=\"noreferrer noopener\" href=\"http:\/\/dx.doi.org\/10.15585\/mmwr.mm6712a2\" target=\"_blank\">http:\/\/dx.doi.org\/10.15585\/mmwr.mm6712a2<\/a>.<\/p>\n\n\n\n<p>[7] Lucier J, Weinstock RS. Type 1 Diabetes. [Updated 2023 Mar 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-.&nbsp;Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507713\/\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507713\/<\/a><\/p>\n\n\n\n<p>[8]Gomez, A. M., &amp; Umpierrez, G. E. (2014). Continuous glucose monitoring in insulin-treated patients in non-ICU settings.&nbsp;<em>Journal of diabetes science and technology<\/em>,&nbsp;<em>8<\/em>(5), 930\u2013936. <a href=\"https:\/\/doi.org\/10.1177\/1932296814546025\">https:\/\/doi.org\/10.1177\/1932296814546025<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chronic Kidney Disease (CKD) Stage 5 of chronic kidney disease (CKD) are one of the leading causes of mortality affecting about 10% of the worldwide population. 38% of patients with CKD are people aged 65 years or older.1 CKD patients have a glomerular filtration rate (GFR) of less than 60mL\/min\/1.73m2. Another indicator is the levels &hellip; <a href=\"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/introduction\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Background<\/span><\/a><\/p>\n","protected":false},"author":494,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-70","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/pages\/70","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/users\/494"}],"replies":[{"embeddable":true,"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/comments?post=70"}],"version-history":[{"count":0,"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/pages\/70\/revisions"}],"wp:attachment":[{"href":"https:\/\/engprojects.tcnj.edu\/chroma-scan-health\/wp-json\/wp\/v2\/media?parent=70"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}